Spray nozzle unit high volume manufacturing at Medspray

Spray nozzle unit manufacturing at Medspray in The Netherlands.

At Medspray in Enschede, The Netherlands, the manufacturing of our soft mist spray nozzle units takes place under clean room conditions on an automated production line, upscaled for high volumes. Several robotic machines assemble the silicon nozzle plates into their plastic holders. The nozzle plates are made of the same material that is used to make computer processor or memory chips, only in this case it is only a mechanical structure, no electronics are involved. The dimensions are mind-boggling tiny, each spray nozzle plate has approximately 100 pores of 2 micron, which is 35 x smaller than the diameter of a human hair. The pores are located on 50 micron diameter membranes of less than 1 micron thickness, to reduce the viscous losses and to keep the spray pressures in our inhaler devices to a minimum.

The resulting spray nozzle units are being assembled into our soft mist inhaler devices. Each spray nozzle unit is tested in line at Medspray to ensure the required quality. When Resyca’s purely mechanical soft mist inhaler devices push the aqueous formulation through these nozzle pores, Rayleigh jets emerge, resulting in 4 micrometer diameter primary droplets, resulting in a slow moving inhalable aerosol cloud. The high-tech nozzle technology enables relatively low-tech inhaler devices, which work purely mechanical and at a relatively low pressure of around 25 Bar.